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|
Gene (polymorphism)
|
R2
|
ΔR2
|
% additional explained variance
|
P value
|
|---|
|
HD CAG
|
.308
|
-
| |
< .0005
|
|
HD CAG + MTHFR A1298C
|
.304
|
.004
|
-
|
.850
|
|
HD CAG + MTHFR C677T
|
.305
|
.003
|
-
|
.590
|
|
HD CAG + compound heterozygotes
|
.304
|
.004
|
-
|
.828
|
- Variance in age at onset for the CAG repeats is indicated as such as well as in combination with the different polymorphisms examined. R2 illustrates the relative improvement of the regression model when the various genotypes are considered in addition to the HD CAG repeats, ΔR2 values quantify these differences. P values refer to R2.
